TPX-0005 Coated Slide

TPX-0005 Coated SlideTPX 0005 is a novel ALK ROS1 TRK inhibitor with the IC50 values of 1. 01 nM for WT ALK, 1. 26 nM for ALK(G1202R), and 1. 08 nM for ALK(L1196M); also a potent SRC inhibitor (IC50 5. 3 nM).

Coelenterazine is a luminescent enzyme substrate

mTOR inhibition and FKBP12 binding is similar to rapamycin

is converted to NAD+ by nicotinamide mononucleotide adenylyltransferase

including other mGlu subtypes

a purine antimetabolite

a major metabolite of curcumin

displaying substantial biochemical activity only against BRD9

or n-butanol of the seed extract of Psoralea corylifolia L

belonging to the family of ketones

Salicin is a phenol

c-Kit and c-Fms with IC50 of 10 nM

Cinnamyl acetate is a naturally occuring compound used as a flavouring agent