Rabusertib (LY2603618) 24/29

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Description

Rabusertib (LY2603618) 24/29Rabusertib (LY2603618) is a highly selective Chk1 inhibitor with potential anti tumor activity in a cell free assay. IC50=7 nM, showing approximately 100 fold more potent against Chk1 than against any of the other protein kinases evaluated.

inhibits DNMT1 activity through ubiquitin-targeted degradation

Levosimendan is a calcium sensitizer acting through calcium-dependent binding to cardiac troponin C (cTnC)

Corning 96 Well Half Area Black with Clear Flat Bottom Polystyrene NBS Microplate

Interactive formula making the mode of the AS

Clozapine is an atypical antipsychotic drug by acting as a 5-HT antagonist

Fosinopril Sodium is the ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor

4 nM and 1

Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 with IC50 of 40 nM in a cell-free assay

PD 128907 HCl is a potent and selective dopamine D3 receptor agonist

Gemcitabine HCl is a DNA synthesis inhibitor with IC50 of 50 nM

with 50-fold greater potency than CDKs

Non Sterile

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